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South node of the moon, Ketu, is a shadow planet know for isolation, spirituality and letting go of material gains, but in 2nd house the south node of the moon gives lots of wealth, separation from family for various reasons, but ketu in the 2nd house makes a person not wanting to have wealth, which is why they get it, there speech is also very powerful and spiritual, however, they tend to isolate themselves through their speech. But, Ketu aspects 5, 7th and 9th place from itself, so it runs away from conflicts, enemies, and debts, while Ketu inquires unusual, undetectable type of disease. When it aspects the 8th house it gives gains and resources of other people's wealth, as in other people will help you gain wealth and assets since past life you were making money on your own while in this life you will enjoy other people's assets. Ketu also aspects the 10th house from 2nd house, where it makes a person a researcher, analyst, spiritual guidance and someone who becomes a film critic.
In western astrology There is no south node, most of the time western astrologer only consider the north node of the moon Rahu. Rahu = Uranus, while Ketu = Neptune. Neptune represents isolation just like Ketu, this is why in vedic jyotish you do not need to look at Neptune or Uranus, and they are too far for their magnetic pull to effect humans on earth. Ketu is all about spirituality and finding the truth, so these people are not attached to family as much even though they love their family and family history. The are about living in isolation or in foreign lands.